Pulmonary and central nervous system aspergillosis in a patient with COVID-19 infection

Introduction. Patients with COVID-19 infection are vulnerable to a variety of serious complications, including invasive fungal infections such as aspergillosis. Because pulmonary aspergillosis is difficult confirm perfect confidence, it has been classified ?proven,??probable,? and ?possible.? We present patient in whom ?probable? was complicated by hematogenous spread into brain formation multiple abscesses. Case outline. A 67-year-old female diagnosed using polymerase chain reaction (PCR) from nasopharyngeal swab. The had never vaccinated before. Despite standard therapy noninvasive oxygen support, the patient?s health deteriorated one month following onset disease, chest discomfort, cough, hemoptysis. Thoracic computed tomography (CT) revealed bilateral infiltrative lesions varying diameters cavities, primarily left lung, well modest effusions both pleural spaces. Aspergillus hyphae were isolated tracheobronchial aspirates. Amphotericin B, which only available antifungal medication at time, fell coma. CT scan skull several inside brain, some cavities suggestive metastatic abscesses, most likely etiology (Aspergillus) result all other precautions, died. autopsy not carried out. Conclusion. In addition patients may develop aspergillosis, can be fatal because possibility brain.